About traumatic brain injury (TBI)
What is TBI?
Traumatic brain injury (TBI) is defined as a structural alteration of brain function caused by external causes. It constitutes a true silent epidemic, since the impact of its consequences is really unknown.
Estimated incidence in Europe:
More information of TBI
Approximately 80% are defined as “mild TBI”, which although they require assistance in the emergency services and generally the performance of a cranial computed tomography (CT), they represent a relatively good prognosis, although it has been described that up to 20% may suffer long-term sequelae despite initially normal imaging test
Quick determination of biomarkers to rule out brain injuries in mild traumatic brain injury:
First multicenter study using a point of care instrument in trauma and pediatric emergency services.
WHY IS SO IMPORTANT?
Previous results of studies carried out by our group show that the H-FABP biomarker can, with 95% sensitivity, reduce by 30% the number of CT scans performed.
Resources would be saved and patients undergoing potentially damaging imaging would be avoided.
Which other goals aim to be reached?
- To assess the feasibility of measuring quickly H-FABP using a Point of Care (POC) device in patients with mild TBI and to relate its levels to the presence of lesions on cranial CT.
- To assess the utility of performing serial H-FABP determinations in patients with initially pathological CT and to relate it to the prognosis of TBI.
- To assess whether the incorporation of new biomarkers improves the prediction of brain damage that can be done with H-FABP.
- Develop and validate a POC device capable of measuring various markers of brain damage in minutes in emergency departments
- Demonstrate that this device is also useful in the management of TBI in pediatric age.
The Macarena Neurovascular group, selected by Fundación Mutua Madrileña for its research grant
It is created a device that detects minor brain injuries with a drop of blood
Is it possible to diagnose a brain injury with just a drop of blood?
The Neurovascular group of the Macarena Hospital selected by the Fundación Mutua Madrileña to allocate its Research Grant